Fungal Microbiome; Mycobiome
نویسندگان
چکیده
Bakteriyel mikrobiyom analiz ve araştırmaları, mantar mikrobiyomu kavramı çalışmalarının önüne geçmiştir. Tüm insanlar laboratuvar hayvanları, sağlıklı olduklarında doğal topluluklarını taşırlar. Mantar mikrobiyomu, bakteriyel mikrobiyomdan önemli ölçüde daha küçüktür. Hastalıkta kofaktör olarak mikrobiyomunun rolü de belirgindir ancak bunca zamanda hafife alınmıştır. Sağlıklı bir derinin fungal mikrobiyomunda yer alan başlıca türler Malassezia Candida türleridir. deride fazla maya formu görülürken, etkilenen bölgelerde çok hifal formda görülmektedir. Ağız fungi içerdiği kabaca Candida, Aspergillus, Fusarium Cryptococcus sp den oluşmaktadır. akciğerlerin steril olduğu savı da son yıllarda yapılan sekans çalışmaları ile değişmiş, topluluklardan Aspergillus fumigatus başta olmak üzere Ceriporia lacerata, Saccharomyces cerevicae Penicillium brevicompactum’un bulunduğunu gösterilmiştir. İnflamatuar bağırsak hastalıklarında belirgin mikrobiyal disbiyoz bulunmuş, Basidiomycota / Ascomycota oranı C. albicans’ın arttığı, cerevisiae oranının ise azalmış belirlenmiştir. Sonuçta; Bu tür karmaşık birbirine bağlı sistemlerde, mikobiyom, dizi hastalığa bunların patogenezine katkıda bulunan faktör olabilir. İleri çalışmalar kısa sürede bu konulara açılım getirecektir.
منابع مشابه
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ژورنال
عنوان ژورنال: Journal of biotechnology and strategic health research
سال: 2021
ISSN: ['2587-1641']
DOI: https://doi.org/10.34084/bshr.919990